SGO Issues November 6, 2014
SGO, ACOG release Practice Bulletin on Lynch syndrome
Annual Meeting early bird registration now open
Choosing Wisely resources on SGO website
Nov. 16 deadline extension for Board/Council nominations
Deadline extended to Nov. 9 for Foundation awards
Winter Meeting abstract submission deadline Nov. 10
Globe-athon 2014 achieves awareness milestones
This month SGO and the American College of Obstetricians and Gynecologists (ACOG) released a Practice Bulletin on Lynch syndrome. The Practice Bulletin was developed by ACOG’s Committee on Practice Bulletins—Gynecology and SGO’s Lynch Working Group on behalf of the SGO Clinical Practice Committee.
The writing group was led by Lee-may Chen, MD, at the UCSF Helen Diller Family Comprehensive Cancer Center in San Francisco, CA. SGO member contributors included David E. Cohn, MD; David A. Fishman, MD; Randall K. Gibb, MD; David G. Mutch, MD; Alexander B. Olawaiye, MD; and David E. Soper, MD, with editorial assistance from Karen H. Lu, MD, and Noah D. Kauff, MD.
Lynch syndrome is the most common inherited cause of both endometrial and colorectal cancer and accounts for 3-5% of both of these diseases. Women with Lynch syndrome have a 40-60% lifetime risk of both endometrial and colorectal cancer. Men with Lynch syndrome have up to an 80% lifetime risk of colorectal cancer. There are, however, proven strategies to significantly reduce the risk of Lynch-associated cancer and mortality if individuals at risk can be identified.
Dr. Chen said that the new Practice Bulletin expands the strategy of the 2004 Bethesda Guidelines for screening for Lynch syndrome, which discussed identification of Lynch syndrome in individuals with colorectal cancer using microsatellite instability (MSI) testing. The new Practice Bulletin, in addition to addressing colorectal cancer, identifies individuals with endometrial cancer who should be evaluated for the possibility of Lynch syndrome using either MSI testing or immunohistochemistry (IHC)-based approaches. Further, it outlines a strategy for assessing women who have a family history suggestive of Lynch syndrome, but who do not have a personal history of cancer.
“Along with the SGO clinical practice statement on evaluating endometrial cancer patients for Lynch, this Practice Bulletin will hopefully go a long way in creating a systematic way to evaluate endometrial cancer patients and their family members for hereditary cancer risk,” she said.
“The Practice Bulletin also outlines proven screening and risk-reduction approaches for individuals identified as having Lynch syndrome,” added Dr. Kauff from Memorial Sloan Kettering Cancer Center. “Colonoscopy every one to two years has been shown to reduce the risk of colorectal cancer death by at least 65 percent in individuals with Lynch syndrome. Risk-reducing hysterectomy with bilateral salpingo-oophorectomy after child-bearing is complete has also been shown to markedly reduce the risk of gynecologic cancers in this syndrome.”
“If practitioners are able to work with their pathologists to routinely perform immunohistochemistry on patient’s endometrial tumor tissue, and also work with their genetic professionals in reviewing a woman’s family cancer history, we hope that high-risk patients can be identified, with additional cancer deaths averted,” said Dr. Chen. “As gynecologic oncologists, we lead the treatment for women with endometrial cancer. The Practice Bulletin gives a practical summary of facts, guidelines, and strategies of identifying and managing gynecologic issues of women with Lynch syndrome.”
Early bird registration for SGO’s 2015 Annual Meeting on Women’s Cancer is open until Monday, Jan. 26, 2015. Member/non-member fees and online registration are available on the SGO website. SGO Chicago-based members and staff have extended a special video invitation to all SGO members to “See You in Chicago” March 28-31.
SGO has partnered with Consumer Reports to develop patient-friendly articles and office posters in English and Spanish about the first recommendation advising against screening low risk women with CA-125 or ultrasound for ovarian cancer. In addition to these patient resources, SGO’s Choosing Wisely recommendations are included on related Wikipedia pages and in a new health monitoring app called iTriage app.
If you are interested in serving on the SGO Board/Foundation Council, please review the nomination and election process information and complete the self-nomination form. The deadline to submit an application for a position on the Board has been extended to Sunday, Nov. 16, at 11:59 p.m. ET.
Full SGO members who wish to nominate fellow members for the Harry Long Award or Humanitarianism and Volunteerism Award may email nomination forms to firstname.lastname@example.org. The deadline to submit nominations has been extended to Sunday, Nov. 9, at 11:59 p.m. ET.
Young investigators have until Nov. 10 to submit research for consideration for presentation in a special Poster Session at the 2015 SGO Winter Meeting at Snowbird Resort Feb. 19-21, 2015, in Snowbird, UT. Acceptance letters will be sent out in mid-December.
The second annual Globe-athon to End Women’s Cancers in September united 71 countries to raise awareness of gynecologic cancers. More than 200 awareness events were held around the world, including runs and educational sessions.
Participants pledged to set a goal of taking 10,000 steps during September to bring attention to gynecologic cancers, and over 111.9 million steps were logged for the Globe-athon STEPtember Pledge.
Social media also drove unprecedented awareness and engagement to the Globe-athon cause. The Globe-athon Facebook page now has over 64,000 followers (a more than 1,894 percent increase from 2013) and 11.6 million people were reached with messages on Facebook and Twitter (a 4,317 percent increase from the previous year).
For more information, visit the Globe-athon website.