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SGO/ACCC Joint Education Collaborative: Optimizing Outcomes in Ovarian Cancer Using Personalized Medicine

 

Executive summary

The Society of Gynecologic Oncology (SGO) and the Association of Community Cancer Centers (ACCC) have been awarded a joint independent medical education grant from AstraZeneca and Merck. Together, SGO and ACCC will offer four accredited webinars (live and enduring) and up to six additional non-accredited media presentations (podcasts, clinical reviews) on the topic of delivering personalized medicine in a community setting. The webinar/virtual media programs are expected to launch in June 2021 and offered on a monthly rotation over the course of the year.

nOW aVAILABLE –

“Ovarian Cancer Genetic Labs Physician/Patient Postcard”

Every patient with ovarian cancer should be offered testing aimed at informing targeted therapeutic decisions. This quick-reference, non-exhaustive guide provides a snapshot of germline and somatic testing options available for patients with ovarian cancer. Physicians and patients alike are encouraged to reference this PDF to printable postcard for more information about various labs, counseling options, and insurance information.

“Real-World Palliative Care in GYN Oncology: WHO (can do it), WHAT (is it), WHEN (to start), WHERE (can we do this) and WHY (is it so important)”

A round table discussion with a range of experts from academic centers to small community practice present examples of integrating palliative care in a variety of practice settings.

Moderator: Melissa Hardesty, MD, Alaska Women’s Cancer Care,

Speakers: Linda Smith, MD, Alaska Women’s Cancer Care, Kate Lally, MD FAAHPM, Dana Farber Cancer Institute, Carolyn Lefkowits, MD, MPH, UC Health Cancer Care, Lori Spoozak, MD, MHS, FACOG, FACS, University of Kansas, and Michael Pearl, MD, FACOG, FACS, FAAHPM, Stony Brook University Hospital.

“Conversations in The Clinic: Patient Perspectives on Genetic Testing” Podcast

Listeners will learn about the importance of genetic testing for ovarian cancer from a genetic counselor and a physician, and most importantly, from a patient.

Moderator: Ashley Stuckey, MD

Speakers Todd Tillmanns, MD, FACOG, West Cancer Center, and Leigha Senter-Jamieson, MS, LGC, Ohio State College of Medicine

“Perfecting Placement of PARPS: Preventing Progression of Ovarian Cancer Webinar”

In the fast-paced world of PARP inhibitor approvals in both the setting of maintenance and therapy in ovarian cancer, this panel of experts will assist practitioners to understand how to order germline and somatic testing for BRCA and HRD mutations. Speakers will discuss sequencing of PARP inhibitors as well as mitigating side effects. Additionally, they will discuss future directions for the use of PARP inhibitors as well as briefly discuss resistance to PARP inhibitors.

Moderator: John Farley, MD, COL, FACOG, FACS, Dignity Health – Cancer Institute, St. Joseph’s Hospital and Medical Center

Speakers: Premal Thaker, MD, MS, Washington University in St. Louis Siteman Cancer Center, Mary (“Maggie”) Mullen, MD, Washington University in St. Louis School of Medicine, and Todd Tillmanns, MD, FACOG, West Cancer Center

Podcast: Personalized Medicine in Ovarian Cancer: It’s Finally Time

This podcast focuses on individualized treatment in ovarian cancer.  Case based scenarios are used to help facilitate discussion on targeted therapy for clear cell, low grade serous, and high grade serous ovarian cancers.

“A Personalized Approach to Patients Diagnosed with Advanced or Recurrent Ovarian Cancer On-Demand Webinar”

This webinar is dedicated to helping healthcare professionals treating patients with newly diagnosed ovarian cancer choose between neoadjuvant chemotherapy or upfront surgery. The webinar also reviews the role of secondary cytoreduction in patients with recurrent ovarian cancer.

New Antineoplastic Therapy Flashcards: Management and Treatment of Side Effects in Practice

Together, SGO and ACCC have created unique tools aimed at enhancing the delivery of personalized medicine in a community setting. The Chemotherapy & Targeted Therapy Subcommittee of the SGO Education Committee previously developed flash cards that highlight therapies which may be used less frequently and offer a “refresher” on dosing, side effects, contraindications, and more. This current batch of flash cards expands on this project and provides up-to-date information on some key drug options for patients with ovarian cancer.

Included in this resource are individual PDFs on the following:

  • Niraparib
  • Olaparib
  • Pemetrexed
  • Rucaparib
  • Sorafenib
  • Trametinib

Recognizing and Mitigating Health Care Disparities in Ovarian Cancer: The Community Cancer Experience On-Demand Webinar

Significant disparities in ovarian cancer exist across the spectrum of care. More specifically, decreased survival, advanced stage at diagnosis, adherence to guideline concordant care, and undergoing genetic testing all may be influenced by factors such as race/ethnicity, insurance status, socioeconomic status, hospital characteristics and rurality.

Speakers: Mazen Khalil, MD, St. Bernards Cancer Center; Jeffrey Hines, MD, University of Connecticut Health System; Mandy Gordon, APRN, St. Bernards Cancer Center; Todd Tillmanns, MD, FACOG, West Cancer Center; Leigha Senter, MS, LGC, The Ohio State University

Moderator: William Burke, MD, Stony Brook Medicine

Coming Soon

Best of ESMO Podcast

  • Will be available on SGO Connect Ed in December 2022
  • Moderator: Dr. Ashley Stuckey
  • Speakers:
    • Dr. Paul DiSilvestro to update SOLO1 7-year survival data
    • Dr. Premal Thaker to present PAOLA data
    • Dr. Sarah Friedman to provide a summary on novel early phase drugs

Steering committee –

  • William Burke, MD, Stony Brook University Cancer Center
  • Melissa Hardesty, MD, MPH, Alaska Women’s Cancer Care
  • Premal Thaker, MD, MS, Washington University in St. Louis, Siteman Cancer Center
  • Ashley Stuckey, MD Brown University, Women and Infants Hospital
  • Todd Tillmanns, MD, FACOG, West Cancer Center
  • Jeff Lin, MD, City of Hope Medical Group
  • Roisin O’Cearbhaill, MD, Memorial Sloan Kettering Cancer Center
  • Charles Drescher, MD, Swedish Cancer Institute
  • John Farley, MD, COL, FACOG, FACS, Dignity Health Cancer Institute, St. Joseph’s Hospital and Medical Center
  • Leigha Senter-Jamieson, MS, LGC, The Ohio State University Wexner Medical Center

 

Target Audience

The target audience for this initiative includes medical oncologists, gynecologic oncologists, obstetrician-gynecologists, primary care physicians, advanced practice providers (nurse practitioners, physician assistants, oncology pharmacists), oncology nurses, pathologists, and other healthcare professionals (HCPs) involved in treating patients with ovarian cancer.

Learning Objectives

At the end of this educational initiative, participants should be able to:

  • Discuss the utility of novel biomarkers such as homologous repair deficiency (HRD) genomic instability for personalizing therapy in patients with ovarian cancer
  • Assess the clinical rationale for tumor and HRD genomic instability testing, including differentiation of germline/familial risk assessment versus tumor profiling in patients with ovarian cancer
  • Implement monitoring strategies and manage adverse events of emerging targeted therapies for patients with ovarian cancer
  • Explore strategies to improve patient engagement in shared decision-making regarding biomarker testing and personalized treatment in ovarian cancer along the continuum of care

Accreditations

The live/online webinars will each offer the following credits:

  • CME: 0.5 AMA PRA Category 1 Credit(s)™
  • ACPE credit: 0.5 contact hour
  • ANCC credit: 0.5 contact hour

Non-accredited educational materials: podcasts, case reviews, and other educational resources/tools

fellowship

Evaluation and Outcomes

The impact of participating in this initiative on clinical performance related to the optimal management of ovarian cancer will be assessed by comparing the response for pre-activity and post-activity tests (also designed by the Steering Committee). The outcomes analysis will assess the effectiveness of the programs in changing knowledge and competence, and intent to change behavior among learners in the following areas:

  • Learners will have a better understanding of utility of novel biomarkers such as homologous repair deficiency (HRD) genomic instability for personalizing therapy in patients with ovarian cancer
  • Learners will correctly assess the clinical rationale for tumor and HRD genomic instability testing, including differentiation of germline/familial risk assessment versus tumor profiling for therapeutic implications in ovarian cancer patients
  • Learners will be better prepared to monitor and manage adverse events for emerging targeted therapies for patients with and ovarian cancer
  • Learners will be more familiar with implementing strategies to improve engage patients in shared decision-making regarding biomarker testing and personalized treatment in ovarian cancer throughout the continuum of care starting at diagnosis
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Educational materials that are part of accredited education (such as slides, abstracts, handouts, evaluation mechanisms, or disclosure information) must not contain any marketing produced by or for an ineligible company, including corporate or product logos, trade names, or product group messages. This activity has been supported by an independent medical education grant from AstraZeneca and Merck.

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